Knowledge of electrobiological features of excitation of the salivary glands allow to investigate the mechanisms of formation of saliva, synthesis, formation of secretion, the secretory cycle and its phases. Excitation of all excitable structures is accompanied by a depolarization of the cell membrane, but there is the hyperpolarization in glandular tissue. The phenomenon of giperpolarization is also observed in the central nervous system, nerves, muscles. However, it occurs in case of braking (inhibition of the activity of the cell membrane), while the hyperpolarization of glandular cell means its active state. Stimulating potential of hyperpolarization is due to the entrance of chloride ions into the cell and release of sodium and potassium ions from the cell. Heteropolarity of glandular cells is one of the mechanisms of the secretory function.