Лейкоплакия полости рта: клиника, диагностика, лечение

  • № 2 2021

Страницы: 

44

 – 

49

Язык: русский

Открыть файл статьи
Открыть страницу статьи в Интернет

Аннотация

Лейкоплакия довольно распространенная патология слизистой оболочки полости рта, в 20-30% случаев имеющая тенденцию к злокачественному развитию. Эта проблема заставляет стоматологов задумываться об онко-настороженности. На определенных этапах развития лейкоплакия обратима,своевременная диагностика и лечение предупреждают развитие малигнизации. В данной статье содержится обзор текущих данных литературы для оценки клинических и цитологических характеристик лейкоплакии как предракового поражения.

Leukoplakia is a fairly common pathology of the oral mucosa, with a tendency to malignant development in 20-30% of cases. This problem makes dentists think about cancer vigilance. At certain stages of development leukoplakia is reversible,timely diagnostics and treatment can prevent the development of malignancy. This paper includes the review of current data of published literature for the evaluation of clinical and pathological characteristics of leukoplakia as precancerous lesion.

Список использованных источников

  1. Staines K, Rogers H: Oral leukoplakia and proliferative verrucous leukoplakia: A review for dental practitioners. BD J 223:655-661, 2017 https://doi.org/10.1016/j.denabs.2018.03.022
  2. NA Karpuk, SP Rubnikovich, IV Samsonova.Метод вторичной медицинской профилактики предопухолевых заболеваний слизистой оболочки рта// Stomatologist.-2020; 1(36):66-75 https:// doi.org/10.32993/stomatologist.2020.1(36).12
  3. E.V. Goloub, T.G. Shkavrova, V.V. Polkin et al.Молекулярно-цитогенетические нарушения в клетках слущенного эпителия у больных раком слизистой оболочки полости рта/ E.V. Goloub, T.G. Shkavrova, V.V. Polkin, G.F. Mikhailova,V.V. Tsepenko, F.E. Sevryukov, V.S. Medvedev,P.A. Isaev// Nauchno-prakticheskii zhurnal «Patogenez».-2019; 4 (17):69-77 https://doi.org/10.25557/2310-0435.2019.04.69-77
  4. R Mamedov, B Gamzaev, A Alizade, L Ibragimova.Condition of dental adult status in relation to oral mucosa diseases// Actual problems in dentistry.-2013;9(6):18-21 https://doi.org/10.18481/2077- 7566-2013-0-6-25-30
  5. van der Waal I. Potentially malignant disorders of the oral and oropharyngeal mucosa; terminology,classifi cation and present concepts of management.Oral Oncol. 2009;45:317-323. https://doi. org/10.1016/j.oraloncology.2008.05.016
  6. Nanda KD, Ranganathan K, Devi U, Joshua E. Increased expression of CK8 and CK18 in leukoplakia, oral submucous fi brosis,and oral squamous cell carcinoma: an immunohistochemistry study. Oral Surg Oral Med Oral Pathol Oral Radiol. 2012;113:245-253. https://doi.org/10.1016/j.tripleo.2011.05.034
  7. Feng JQ, Mi JG, Wu L, Ma LW, Shi LJ, Yang X, Liu W, Zhang CP, Zhou ZT. Expression of podoplanin and ABCG2 in oral erythroplakia correlate with oral cancer development. Oral Oncol.2012;48:848–852. https://doi.org/10.1016/j.oraloncology.2012.03.015
  8. Qin GZ, Park JY, Chen SY, Lazarus P. A high prevalence of p53 mutations in premalignant oral erythroplakia. Int J Cancer. 1999;80:345–348. https://doi.org/10.1002 /(sici)1097-0215(19990129)80:3%3C345::aidijc2% 3E3.0.co;2-n
  9. JBánóczy. The Therapy of Oral Leukoplakia//Oral Leukoplakia.- 1982:182-189 https://doi.org/10.1007/978-94-009-7564-4_9
  10. Punyani SR, Sathawane RS. Salivary level of interleukin-8 in oral precancer and oral squamous cell carcinoma. Clin Oral Investig. 2013;17:517–524https://doi.org/10.1007/s00784-012-0723-3
  11. Greer RO. Pathology of malignant and premalignant oral epithelial lesions. Otolaryngol Clin North Am. 2006;39:249–275, v. https://doi. org/10.1016/j.otc.2005.11.002
  12. Warnakulasuriya S, Johnson NW, van der Waal I. Nomenclature and classifi cation of potentially malignant disorders of the oral mucosa. J Oral Pathol Med. 2007;36:575–580https://doi.org/10.1111/j.1600-0714.2007.00582.x
  13. Batsakis JG, Suarez P, el-Naggar AK. Proliferative verrucous leukoplakia and its related lesions. Oral Oncol. 1999;35:354–359.https://doi.org/10.1016/s1368-8375(99)00007-x
  14. Chen YW, Lin JS, Fong JH, Wang IK, Chou SJ, Wu CH, Lui MT, Chang CS, Kao SY. Use of methylene blue as a diagnostic aid in early detection of oral cancer and precancerous lesions. Br J Oral Maxillofac Surg. 2007;45:590–591. https://doi.org/10.1016/j.bjoms.2006.08.017
  15. Ribeiro AS, Salles PR, da Silva TA, Mesquita RA. A review of the nonsurgical treatment of oral leukoplakia. Int J Dent. 2010;2010:1-10 https://doi.org/10.1155/2010/186018
  16. Kawczyk-Krupka A, Waśkowska J, Raczkowska-Siostrzonek A, Kościarz-Grzesiok A et.al.Comparison of cryotherapy and photodynamic therapy in treatment of oral leukoplakia/ Kawczyk- Krupka A, Waśkowska J, Raczkowska-Siostrzonek A, Kościarz-Grzesiok A, Kwiatek S, Straszak D,Latos W, Koszowski R, Sieroń A// Photodiagnosis Photodyn Ther.2012;9:148–155https://doi. org/10.1016/j.pdpdt.2011.12.007
  17. Gorsky M, Epstein JB. The effect of retinoids on premalignant oral lesions: focus on topical therapy. Cancer. 2002;95:1258–1264. https://doi.org/10.1016/s1368-8375(98)80010-9
  18. Reichart PA, Philipsen HP. Oral erythroplakia-a review. Oral Oncol. 2005;41:551–561.https://doi.org/10.1016/j.oraloncology.2004.12.003
  19. Hashibe M, Mathew B, Kuruvilla B, Thomas G, Sankaranarayanan R, Parkin DM, Zhang ZF. Chewing tobacco, alcohol, and the risk of erythroplakia. Cancer Epidemiol Biomarkers Prev. 2000;9:639–645https://doi.org/10.1023/a:1013991025848
  20. Villa A, Villa C, Abati S. Oral cancer and oral erythroplakia: an update and implication for clinicians. Aust Dent J. 2011;56:253–256https:// doi.org/10.1111/j.1834-7819.2011.01337.x
  21. I Al-Hashimi. Editorial: Advances in the Diagnosis and Management of Oral Diseases// The Open Pathology Journal.-2011;5(1):1-2 https://doi.org/10.2174/1874375701105010001
  22. Gazhva SI. Modern methods of treatment of diseases of the mucous membrane and red border of the lips / SI Gazhva , AV Woodpecker, OS Nadeykina // Scientifi c Review. Medical sciences.–2015; 1: 121-121. URL: https://sciencemedicine.ru/ru/article/view?id=709van der Waal I.
  23. Potentially malignant disorders of the oral and oropharyngeal mucosa; terminology, classifi cation and present concepts of management. Oral Oncol.2009;45:317-323. https://doi.org/10.1016/j. oraloncology.2008.05.016
  24. Vlková B, Stanko P, Minárik G, Tóthová L, Szemes T, Baňasová L, Novotňáková D, Hodosy J, Celec P. Salivary markers of oxidative stress in patients with oral premalignant lesions. Arch Oral Biol . 2012; 57: 1651-1656. https://doi.org/10.1016/j. archoralbio.2012.09.003
  25. Steele T.O, Meyers A. Early detection of premalignant lesions and oral cancer. Otolaryngol Clin NorthAm. 2011; 44: 221-229. https://doi. org/10.1016/j.otc.2010.10.002
  26. Krahl D, Altenburg A, Zouboulis CC. Reactive hyperplasias , precancerous and malignant lesions of the oral mucosa. J Dtsch Dermatol Ges .2008; 6: 217-232. https://doi.org/10.1111/j.1610- 0387.2007.06625.x
  27. Pietruska M, Sobaniec S, Bernaczyk P, Cholewa M, Pietruski JK, Dolińska E, Skurska A.,Duraj E., Tokajuk G. Clinical evaluation of photodynamic therapy effi cacy in the treatment of oral leukoplakia. Photodiagnosis and Photodynamic Therapy. 2014; 11: 34–40. https:// doi.org/10.1016/j.pdpdt.2013.10.003
  28. Bánóczy J, Gintner Z, Dombi C. Tobacco Use and Oral Leukoplakia. J Dent Educ, 2001;65: 322–327. https://doi.org/10.1002/j.0022- 0337.2001.65.4.tb03402.x
  29. Kamilov Kh.P. , Kadirbaeva AA, Aripova D.U.Early detection of oral precancerous diseases//Journal of Medicine and Innovations, 2021; 1:146-149
  30. Kamilov Kh.P. , Kadirbaeva AA, Musaeva KA Screening diagnostics of oral precancerous diseases.// American Journal of Medicine and Medical Sciences, 2019; 9 (6):194-196.http://article.sapub.org/10.5923.j.ajmms.20190906.04.html. Accessed November 18, 2020
  31. Aahman, E. The global burden of disease :2004 update / E. Aahman et al. –World Health Organization : WHO Press, 2008. – 160 р

Список всех публикаций, цитирующих данную статью