Актуальность этиологии и патогенеза хронического рецидивирующего афтозного стоматита (обзор литературы)

  • № 3(72) 2018

Страницы: 

41

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46

Язык: русский

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Аннотация

Хронический рецидивирующий афтозный стоматит (ХРАС) представляет серьезную проблему в связи со сложностью патогенетических механизмов развития, системностью поражения организма, сложностью ведения пациентов. Иммунологические изменения, наблюдаемые у пациентов с ХРАС, в целом представляют собой традиционную динамику реализации мукозального клеточно-опосредованного иммунного ответа, во многом являются реактивными для афт, недостаточно обоснованы как этиологически значимые. На современном этапе существует большое количество средств и методов лечения ХРАС, однако полный алгоритм комплексной терапии не разработан, отсутствуют методики поддерживающей терапии, что требует дальнейших исследований.

Any common mechanisms for RAS and gastrointestinal diseases are not proposed in publications, that is why, lastmention may be predisposes factors. Previous studies at RAS, in principle, have suggested cell-mediated activation of immune response – common for mucosa, they have pathogenetic and reactive meaning, but it is early to interpret that as an etiology. Various treatment modalities are used, but no therapy is defi nitive at RAS. Systemic medications can be tried if topical therapy is ineffective. Ethiology and pathogenesis of recurrent aphthous stomatitis still actually.

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